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Aims of the study:
Both DAN-PSS and IPSS have been developed for evaluation of lower urinary tract
symptoms (LUTS) in patients having benign prostatic enlargement. It has been
shown that these scores have strong correlation when used to assess symptomatology
in these patients. However, neither of these is disease specific. We aimed to
study whether there is any correlation between these scores when assessing symptoms
among men whose symptomatology was obviously caused by other reason than symptomatic
BPH.
Methods:
The sample was gathered from the patient registers of two University Hospitals.
A questionnaire was mailed to all patients who were operated between years 1963-1973
for undescended testis, hypospadia, inguinal hernia or acute appendicitis in
their childhood. The questionnaire was mailed to subjects operated for hypospadia.
The sample was 646 men. For DAN-PSS three scores were calculated. 1) For DAN-PSS
prevalence the scale of the frequency score of each symptom (part A of the question)
was changed to 0='No, there are no symptoms' and 1='Yes, there are symptoms'.
The score was then calculated by adding these values of all the twelve questions.
The possible values of DAN-PSS prevalence score therefore ranged from 0 to 12.
2) DAN-PSS frequency was calculated by adding the frequency scores of each symptom.
The possible values of DAN-PSS frequency score therefore range from 0 to 36.
3) DAN-PSS total was calculated by multiplying the frequency score by the trouble
score of each symptom, and then adding the resulting figures. The possible values
of DAN-PSS total therefore ranged from 0 to 108. For IPSS two scores were calculated.
1) For IPSS prevalence the scale of the frequency score of each symptom was
changed to 0='No, there are no symptoms' and 1='Yes, there are symptoms'. The
variable was then calculated by adding the values of all questions. The possible
values of IPSS prevalence therefore ranged from 0 to 7. 2) IPSS total was calculated
by adding the frequency scores of all questions. The possible values of IPSS
total therefore ranged from 0 to 35. For comparison of IPSS and DAN-PSS questionnaires
five additional scores were calculated by using questions that measured the
same symptoms (ie. incomplete emptying of the bladder, frequency, urgency, weak
stream, straining and nocturia Selected DAN-PSS prevalence score was calculated
by adding the yes/no values of part A of the questions 2, 3, 4, 5, 6 and 7.
The possible values of Selected DAN-PSS prevalence therefore ranged from 0 to
6. Selected DAN-PSS frequency score was calculated by adding the frequency scores
of symptoms 2, 3, 4, 5, 6, and 7. The possible values of Selected DAN-PSS frequency
therefore ranged from 0 to 18. Selected DAN-PSS total was calculated by multiplying
the frequency score by the trouble score of symptoms 2, 3, 4, 5, 6, and 7, and
then adding the resulting figures. The possible values of Selected DAN-PSS total
therefore ranged from 0 to 54. Selected IPSS prevalence score was calculated
by adding the yes/no values of the symptoms 1, 2, 4, 5, 6 and 7. The possible
values of Selected IPSS prevalence ranged from 0 to 6. Selected IPSS total score
was calculated by adding the frequency scores of symptoms 1, 2, 4, 5, 6 and
7. The possible values of Selected IPSS total therefore ranged from 0 to 30.
Results:
There was a statistically significant positive correlation between the DAN-PSS
and IPSS symptom scores irrespective of the score type. The correlation was
at weakest when the all questions were included and the DAN-PSS score also included
the trouble caused by the symptom. The strongest association was detected when
DAN-PSS included only same symptoms as IPSS (Table 1). Correlation analysis
of DAN-PSS and IPSS
|
SCORE |
Spearman Correlation Coefficient |
P-value |
|
DAN-PSS prevalence and IPSS prevalence |
0.75 |
0.0001 |
|
DAN-PSS total and IPSS total |
0.70 |
0.0001 |
|
Selected DAN-PSS prevalence and Selected IPSS prevalence |
0.76 |
0.0001 |
|
Selected DAN-PSS total and IPSS total |
0.77 |
0.0001 |
|
DAN-PSS frequency and IPSS total |
0.76 |
0.0001 |
|
Selected DAN-PSS frequency and Selected IPSS total |
0.77 |
0.0001 |
Conclusion:
Correlations were strong indicating that both of these scores measure LUTS similarly
despite of underlying cause. Both of them can be used for evaluation of LUTS.