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Hysterectomy may be total or subtotal (when the cervix is conserved). Total abdominal hysterectomy disrupts the intimate anatomical relationship between the uterus, bladder, bowel and vagina, and it is reasonable to suppose that organ function might be altered by the surgery. It might also be supposed that the less extensive subtotal hysterectomy might alter function to a lesser degree. Which operation causes less disruption to bladder, bowel or sexual function remains contentious.
AIMS:
We conducted a prospective, randomised, and multicentre study of total versus
subtotal hysterectomy to resolve the controversy.
METHODS:
We recruited women who were < 60 years, weighed < 100 KGs, had regular normal
smears and were having hysterectomy for benign indications. Randomisation was
by computer generated random numbers in opaque sealed envelopes and both investigator
and study subjects were "blind" to the operation. Urinary & bowel function were
assessed using designer and validated questionnaires pre-operatively, and at
6 and 12 months post-hysterectomy. Urodynamic studies were conducted at the
same time. All definitions conform to ICS classifications.
RESULTS:
This is an ongoing study. A total of 323 women have been recruited. To date
199 women have completed 12 months follow-up. Of these, 91 women had a subtotal
hysterectomy and 108 had a total hysterectomy. The mean age of the women in
the total hysterectomy group was 44.2 years and in the subtotal group was 44
years. Preoperatively no differences were seen in baseline measures of urinary,
bowel and sexual function. Table 1 shows data for pre and post operative urinary
function after hysterectomy
|
Symptoms |
Total hysterectomy |
Subtotal hysterectomy |
||||
|
|
Pre op |
Postop 6mon |
12 mon |
Pre op |
Postop 6mon |
12 mon |
|
|
n (%) |
n (%) |
n (%) |
n (%) |
n (%) |
n (%) |
|
Frequency |
19 (21) |
17 (7) |
20 (14) |
22 (24) |
19 (23) |
19 (23) |
|
Nocturia |
31 (29) |
12 (12) |
21(23) |
19 (21) |
3 (4) |
10 (22) |
|
SI |
11 (10) |
6 (6) |
8 (9) |
9 (10) |
3 (4) |
7 (8) |
|
UI |
14 (13) |
7 (7) |
10 (11) |
16 (18) |
8 (1) |
8 (10) |
|
Incomplete bladder emptying |
35 (33) |
27 (27) |
19 (21) |
21 (23) |
17 (21) |
11 (13) |
|
Straining |
15 (14) |
9 (9) |
9 (9) |
7 (8) |
3 (4) |
5 (6) |
|
Poor stream |
1 (1) |
3 (3) |
2 (2) |
4 (4) |
0 |
0 |
Analysis was carried out for between group differences on urinary function 6 and 12 months post operatively. Non parameteric tests were used. No significant differences in urinary function between the two groups . When comparing the difference preoperatively, 6 and 12 months postoperatively in both groups stress incontinence was significantly reduced (p< .01) 6 months postoperatively in the total hysterectomy group but failed to reach significance at 12 months. In the total hysterectomy group frequency of micturition reduced significantly at 6 and 12 months postoperatively. In the subtotal group frequency of micturition reduced significantly (<.005) at 6 months but not at one year. However, nocturia reduced significantly (p<.05) at one year. Urodynamic studies were carried out on 188 women preoperatively, 142 women at 6 months and 130 at 12 months. No changes were seen in the urodynamic parameters or bowel function between the two groups and before and after surgery Table 2
|
Symptoms |
Total hysterectomy |
Subtotal hysterectomy |
||||
|
|
Pre op |
Postop 6mon |
12 mon |
Pre op |
Postop 6mon |
12 mon |
|
|
n (%) |
n (%) |
n (%) |
n (%) |
n (%) |
n (%) |
|
Bowel <3/day |
15 (14) |
11 (11) |
14 (15) |
8 (9) |
7 (8) |
7 (8) |
|
Hard stools |
21 (20) |
24 (24) |
18 (20) |
22 (24) |
15 (18) |
19 (23) |
|
Frequent straining |
14 (15) |
20 (20) |
14 (15) |
8 (9) |
10 (11) |
9 (11) |
|
Use of laxative |
3 (3) |
11 (11) |
10 (11) |
8 (9) |
8 (10) |
7 (8) |
|
Urgency |
19 (19) |
22 (22) |
25 (27) |
14 (15) |
21 (26) |
21 (25) |
|
Flatus incontinence |
2 (2) |
4 (4) |
5 (5) |
2 (2) |
2 (2) |
2 (2) |
|
Faecal incontinence |
1 (1) |
0 |
0 |
1 (1) |
0 |
0 |
|
Digitation |
14 (13) |
16 (16) |
9 (10) |
9(10) |
11(4) |
6 (7) |
CONCLUSION:
Contrary to popular belief , neither urinary or bowel function are affected
by total or subtotal hysterectomy.