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Aims of
Study
Ambulatory urodynamic monitoring (AUM) generates data over several hours. Data
is analysed following completion of the study. Little has been published on
the variation in interpretation of these data. This prospective study assesses
the level of agreement between 2 independent observers using a standardised
protocol for the conduct and interpretation of AUM in women presenting with
urinary urgency.
Methods
111 women underwent both AUM and videocystometrography (VCMG) in random order.
VCMG was performed and interpreted according to ICS criteria. AUM was carried
out using the MMS-UPS2020® according to a standardised protocol. Two investigators
(AUM1 and AUM2), blinded to the other's findings and those on VCMG, independently
interpreted the traces along with the subject's urinary diary. No arbitrary
minimum amplitude was set for the detection of detrusor activity, which was
determined by the quality and resolution of the subtracted detrusor pressure
trace itself. DI was only diagnosed if bladder involuntary detrusor activity
overactivity was associated with urgency and /or urge incontinence. GSI was
diagnosed when urine loss was reported and detected in the absence of detrusor
instability. In women with coexistent DI, GSI was only diagnosed when leakage
was reported in the absence of detrusor activity and a positive pad test.
Results
The diagnoses recorded in 100 women completing the study are listed in table
1. AUM2 considered 6 AUM studies to be inadequate for diagnostic purposes. AUM2
also considered these 6 studies and a further 1 study to be inadequate.

Tables 2 and 3 show the agreement for DI and GSI between the 2 observers on AUM and between AUM and VCMG. The inter-observer agreement on AUM for DI and GSI was 87% and 83% respectively.

Conclusions
This is the first prospective study of inter-observer agreement using AUM. Interpretation
according to a standardised protocol, results in a high consistency between
observers. The findings lend further support to the use of AUM as a clinical
tool in the investigation of lower urinary tract function.