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A COMPARISON
OF DETRUSOR MYECTOMY AND ENTEROCYSTOPLASTY FOR DETRUSOR OVERACTIVITY.
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Authors:
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MARTINDALE, A.D. & STEWART,
L.H.
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Institution:
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DEPT. UROLOGY, WESTERN
GENERAL HOSPITAL, EDINBURGH, EH16 6UH.
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AIMS:
Bladder auto-augmentation by partial detrusor myectomy was developed in response
to the well-documented complications of augmentation enterocystoplasty. We aimed
to evaluate and compare the outcome in patients undergoing enterocystoplasty
or detrusor myectomy for detrusor overactivity.
METHODS:
All patients undergoing detrusor myectomy (n=10) or ileocystoplasty (n=10) over
a 28 month period were retrospectively studied. Operations were performed by
a single consultant surgeon and minimum follow up was six months. Diagnosis
was confirmed preoperatively by urodynamic assessment. Seventeen patients had
detrusor instability. Three patients in the ileocystoplasty group were diagnosed
with neuropathic hyper-reflexia. Long term treatment and failure of medical
therapy had lead to consideration for surgery. Morbidity, clinical and urodynamic
outcomes were compared.
RESULTS:
An overall improvement was documented in 70% (7 out of 10) of the detrusor myectomy
group and 90% (9 of 10) of those undergoing ileocystoplasty. Hospital stay was
comparable: Average 8.8 days after myectomy and 8.6 days after ileocystoplasty.
No patients had any persistent bladder leak at post-operative cystogram performed
on average 24 days later. Seven myectomy patients and eight ileocystoplasty
patients required regular intermittent clean self-catheterization after removal
of postoperative indwelling catheter. One patient was unable to perform urethral
self-catheterization following detrusor myectomy, despite preoperative instruction.
This patient underwent Mitrofanoff procedure and eventual ileal conduit diversion.
Major complications were seen in only one patient from each group. A patient
suffered a CVA two days after ileocystoplasty, which resulted in persistent
arm weakness. One patient was readmitted with wound dehiscence ten days after
detrusor myectomy and required re-closure. In the ileocystoplasty group only
one patient reported significant bowel symptoms and only two suffered problems
attributed to mucus production. Three patients required anti-cholinergic medication
after detrusor myectomy. Two of these had no improvement and were offered ileocystoplasty,
but both declined. Urodynamic assessment showed persistent instability in these
three patients. One patient had persistent instability and incontinence after
ileocystoplasty despite an apparently adequate increase in bladder capacity.
CONCLUSIONS:
Success rates and morbidity for both procedures in this study compare well with
published data. After detrusor myectomy only two patients had no appreciable
improvement, either clinically or objectively. In this series detrusor myectomy
appears to compare favourably with ileocystoplasty with regard to morbidity
and outcome. Prospective comparison of the techniques and their long-term outcomes
is required.